Pastitsio (Greek Lasagna) is the ultimate comfort food, perfect for gatherings or cozy dinners at home. This dish features layers of pasta, a rich and spiced meat sauce made with red grape juice and cinnamon, topped with a creamy béchamel sauce that bakes to golden perfection. It’s not just a meal; it’s a hearty experience that brings friends and family together over a shared love for flavor.
Why You’ll Love This Recipe
- Comforting Layers: Enjoy the delightful combination of pasta, meat sauce, and béchamel for a truly comforting dish.
- Rich Flavor: The blend of spices and red grape juice creates a unique depth of flavor that will impress everyone at the table.
- Feeding a Crowd: With 16 servings, this recipe is perfect for large gatherings or meal prep for the week ahead.
- Versatile Ingredients: Easily adjust ingredients to fit dietary preferences or what you have on hand without losing any deliciousness.
- Make Ahead Option: Prepare in advance and bake when ready, making it an ideal choice for busy days.
Tools and Preparation
Before diving into this delightful recipe, gather your essential kitchen tools to ensure a smooth cooking experience.
Essential Kitchen Tools
- Large skillet
- Baking dish (9×13 inches)
- Mixing bowls
- Whisk
- Wooden spoon
- Pot for boiling pasta
Why These Tools Matter
- Large skillet: Perfect for browning the meat and simmering the sauce evenly.
- Baking dish: Ensures even cooking and easy serving of your Pastitsio.
- Whisk: Helps create a smooth béchamel sauce without lumps.
- Wooden spoon: Great for stirring sauces without scratching your cookware.
Ingredients
Pastitsio (Greek Lasagna) is comfort food at its finest, layers of pasta, a rich, spiced meat sauce with red grape juice and cinnamon, and a thick, cheesy béchamel that’s baked to golden perfection. It’s a little effort, a lot of flavor, and exactly what you want when you’re feeding a crowd (or just want killer leftovers).
For the Meat Sauce
- 2 tablespoons olive oil
- 2 pounds lean ground beef
- 1 large red onion (chopped)
- 3 cloves garlic (minced)
- ½ cup red grape juice
- 2 bay leaves
- 1 teaspoon dried oregano (such as Greek or Mediterranean)
- ¼ teaspoon ground cloves
- ½ teaspoon ground cinnamon
- 1 stick cinnamon
- ¼ teaspoon allspice
- salt and pepper (to taste)
- 2 tablespoons tomato paste
- 28 ounce crushed tomatoes
- 1 cup water
- 1 tablespoon sugar
For the Béchamel Sauce
- ½ cup butter (unsalted (8 tablespoons))
- ½ cup all-purpose flour
- 4½ cups milk (2%)
- salt and pepper (to taste)
- ¼ teaspoon ground nutmeg
- ¾ cup Kefalotyri Greek cheese (or Parmesan, grated)
For Assembly
- 2 large eggs
- 2 egg yolks (reserve egg whites for pasta)
- 1 pound Pastitsio pasta (or bucatini)
- ½ cup Kefalotyri Greek cheese
- 2 egg whites
- 1 cup Kefalotyri Greek cheese

How to Make Pastitsio (Greek Lasagna)
Step 1: Prepare the Pasta
Begin by boiling water in a large pot. Add salt to the boiling water before adding the Pastitsio pasta. Cook according to package directions until al dente. Drain and set aside.
Step 2: Make the Meat Sauce
In a large skillet over medium heat:
1. Add olive oil.
2. Sauté chopped onion until translucent.
3. Stir in minced garlic until fragrant.
4. Add ground beef; cook until browned.
5. Mix in red grape juice, bay leaves, oregano, cloves, cinnamon sticks, allspice, salt, pepper, tomato paste, crushed tomatoes, water, and sugar.
6. Simmer on low heat for about 30 minutes.
Step 3: Prepare the Béchamel Sauce
In another pot over medium heat:
1. Melt butter until foamy.
2. Whisk in flour until smooth; cook for about 2 minutes.
3. Gradually add milk while whisking continuously to avoid lumps.
4. Cook until thickened; season with salt, pepper, and nutmeg.
5. Remove from heat; stir in grated Kefalotyri cheese.
Step 4: Combine Egg Mixture
In a mixing bowl:
1. Beat eggs with egg yolks until well combined.
2. Stir in cooled béchamel sauce gradually to temper the eggs.
Step 5: Assemble Pastitsio
In your baking dish:
1. Layer half of the cooked pasta on the bottom.
2. Spread half of the meat sauce over pasta.
3. Repeat layers with remaining pasta and meat sauce.
4. Pour béchamel mixture over top; sprinkle additional grated cheese.
Step 6: Bake
Preheat your oven to 350°F (175°C). Bake uncovered for about 45-50 minutes or until golden brown on top.
Enjoy your homemade Pastitsio!
How to Serve Pastitsio (Greek Lasagna)
Pastitsio is a crowd-pleaser that can be enjoyed in various ways. Whether you’re hosting a special dinner or just enjoying a cozy meal at home, serving suggestions can enhance the experience.
Classic Serving
- Serve warm, directly from the oven for a comforting dish that highlights the layers of pasta and rich meat sauce.
Fresh Salad
- Pair with a simple Greek salad featuring tomatoes, cucumbers, olives, and feta cheese to balance the richness of the pastitsio.
Garlic Bread
- Offer slices of garlic bread on the side for an extra crunch and flavor that complements the soft texture of pastitsio.
Roasted Vegetables
- Include seasonal roasted vegetables for a healthy side that adds color and nutrients to your meal.
Tzatziki Sauce
- A dollop of tzatziki made with yogurt, cucumber, and garlic provides a refreshing contrast to the hearty lasagna.
Lemon Wedges
- Squeeze fresh lemon over your serving for a zesty kick that brightens up the flavors of pastitsio.
How to Perfect Pastitsio (Greek Lasagna)
Creating an exceptional pastitsio requires attention to detail. Here are some tips to elevate your dish.
- Use high-quality ingredients: Fresh herbs, quality meat, and good cheese make a significant difference in flavor.
- Layer wisely: Ensure even distribution of sauce and pasta for balanced bites throughout each serving.
- Let it rest: Allowing pastitsio to sit for 15-20 minutes after baking helps it set and makes slicing easier.
- Experiment with spices: Feel free to adjust the spices according to your preference for a personalized touch.
- Make ahead: Prepare pastitsio in advance and refrigerate. It tastes even better when reheated!
- Garnish thoughtfully: A sprinkle of extra cheese or fresh herbs before serving can enhance presentation and flavor.

Best Side Dishes for Pastitsio (Greek Lasagna)
Pairing pastitsio with complementary side dishes can elevate your meal. Here are some great options:
- Greek Salad
A refreshing mix of cucumbers, tomatoes, olives, and feta cheese tossed in olive oil. - Roasted Potatoes
Crispy on the outside and fluffy on the inside; seasoned with herbs for extra flavor. - Steamed Asparagus
Lightly steamed asparagus adds brightness and crunch; drizzle with lemon juice before serving. - Hummus with Pita Bread
Creamy hummus served with warm pita offers a delightful dip that pairs nicely with pastitsio. - Feta Cheese Dip
Whipped feta blended with olive oil and herbs provides a creamy spread perfect for dipping veggies or bread. - Cucumber Yogurt Salad
A cool cucumber salad mixed with yogurt adds freshness and complements the warm flavors of pastitsio. - Stuffed Grape Leaves (Dolmas)
These flavorful rice-filled grape leaves provide an authentic Greek touch alongside your dish. - Carrot & Celery Sticks
Crunchy raw veggies served with a light dip make for a healthy appetizer before enjoying your main course.
Common Mistakes to Avoid
Making Pastitsio (Greek Lasagna) can be a rewarding experience, but there are common pitfalls to watch out for. Here are some mistakes you should avoid.
- Ignoring the pasta cooking instructions: Always cook the pasta until it’s al dente. Overcooked pasta can turn mushy when baked in the sauce.
- Skipping the seasoning: Don’t forget to season your meat sauce with salt and pepper. Proper seasoning enhances flavor and brings the dish to life.
- Using cold ingredients for béchamel: Make sure your milk is at room temperature before making the béchamel sauce. This helps create a smooth, lump-free sauce.
- Not letting it rest: Patience is key! Allow your Pastitsio to rest for at least 30 minutes after baking. This helps it set and makes slicing easier.
- Overloading on cheese: While cheese is essential, too much can overpower other flavors. Stick to the recommended amounts in the recipe for balance.
Refrigerator Storage
- Store leftovers in an airtight container in the refrigerator.
- Pastitsio (Greek Lasagna) will last up to 3-4 days in the fridge.
Freezing Pastitsio (Greek Lasagna)
- Wrap individual portions tightly in plastic wrap or aluminum foil.
- Place wrapped portions in a freezer-safe container or bag.
- It can be frozen for up to 3 months for best quality.
Reheating Pastitsio (Greek Lasagna)
- Oven: Preheat to 350°F (175°C). Cover with foil and heat for about 25-30 minutes until warmed through.
- Microwave: Heat individual portions on medium power for 2-3 minutes, stirring halfway through for even heating.
- Stovetop: Place slices in a skillet over medium-low heat with a splash of water. Cover and heat until warmed throughout.

Frequently Asked Questions
What is Pastitsio (Greek Lasagna)?
Pastitsio (Greek Lasagna) is a layered dish made with pasta, spiced meat sauce, and creamy béchamel, offering a delightful combination of flavors.
Can I use chicken instead of beef?
Absolutely! You can substitute ground chicken for beef in this recipe while keeping the other ingredients the same.
How do I customize my Pastitsio?
Feel free to add vegetables like spinach or mushrooms into your meat sauce or try different cheeses based on your preference.
Is Pastitsio suitable for meal prep?
Yes! Its flavor improves as it sits, making it perfect for meal prep. Just store it properly in the fridge or freezer.
Can I make this dish gluten-free?
You can use gluten-free pasta alternatives and flour substitutes to make a gluten-free version of Pastitsio.
Conclusion
Pastitsio (Greek Lasagna) is a comforting dish that combines layers of pasta, rich meat sauce, and creamy béchamel into one delicious meal. Its versatility allows you to customize it according to your taste preferences or dietary needs. Don’t hesitate to give this recipe a try; it’s perfect for feeding a crowd or enjoying as delightful leftovers.
Pastitsio (Greek Lasagna)
- Total Time: 1 hour 20 minutes
- Yield: Serves approximately 8 people 1x
Description
Delve into the heart of Greek cuisine with this irresistible Pastitsio (Greek Lasagna). This layered dish features perfectly cooked pasta enveloped in a savory spiced beef sauce, highlighted by the subtle sweetness of red grape juice and a hint of cinnamon. Topped with a creamy béchamel sauce that becomes golden and bubbly in the oven, this comforting meal is perfect for gatherings or cozy dinners at home. With its rich flavors and hearty layers, Pastitsio is not just a dish; it’s an experience that brings people together over a shared love for delicious food.
Ingredients
- 2 pounds lean ground beef
- 1 large red onion (chopped)
- 3 cloves garlic (minced)
- ½ cup red grape juice
- 28 ounces crushed tomatoes
- 1 pound Pastitsio pasta (or bucatini)
- Béchamel sauce ingredients: ½ cup butter (unsalted), ½ cup all-purpose flour, 4½ cups milk (2%), 2 large eggs, 2 egg yolks, ¾ cup Kefalotyri Greek cheese (or Parmesan, grated)
Instructions
- Cook pasta according to package instructions until al dente; drain and set aside.
- In a large skillet, heat olive oil and sauté chopped onion until translucent. Add minced garlic and cook until fragrant.
- Brown the ground beef in the skillet, then stir in red grape juice, crushed tomatoes, spices, and simmer for 30 minutes.
- Prepare béchamel sauce by melting butter, whisking in flour, adding milk gradually until thickened, then mixing in grated cheese.
- In a baking dish, layer half of the pasta followed by half of the meat sauce; repeat layers and top with béchamel sauce.
- Bake at 350°F (175°C) for 45-50 minutes until golden brown.
- Prep Time: 30 minutes
- Cook Time: 50 minutes
- Category: Main
- Method: Baking
- Cuisine: Greek
Nutrition
- Serving Size: 1 slice (200g)
- Calories: 410
- Sugar: 6g
- Sodium: 650mg
- Fat: 22g
- Saturated Fat: 10g
- Unsaturated Fat: 10g
- Trans Fat: 0g
- Carbohydrates: 35g
- Fiber: 4g
- Protein: 20g
- Cholesterol: 120mg



