Chicken and Spinach Casserole with Cream Cheese

Creamy, cheesy, and loaded with comforting flavor, this Chicken and Spinach Casserole with Cream Cheese is the ultimate weeknight dinner. Tender chicken is baked with fresh spinach, garlic, and a luscious cream cheese sauce, then topped with melted mozzarella for a bubbly, golden finish. It’s low-carb, full of protein, and always a hit at the dinner table.

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Why You’ll Love This Recipe
Ultra Creamy – Cream cheese creates a rich, velvety sauce.
Family Favorite – Simple, cheesy, and packed with familiar flavors.
Great for Meal Prep – Reheats beautifully and makes delicious leftovers.
Low-Carb & High-Protein – Great for balanced meals and keto-friendly diets.
One Pan Wonder – Easy prep and cleanup with just a few steps.

Ingredients You’ll Need

For the Casserole:

• 2 cups cooked chicken, shredded or chopped (use rotisserie or leftover chicken)
• 1 tbsp olive oil
• 3 cloves garlic, minced
• 3 cups fresh spinach, roughly chopped
• 1 block (8 oz) cream cheese, softened
• ½ cup sour cream
• ½ cup chicken broth
• 1 tsp onion powder
• ½ tsp garlic powder
• ½ tsp salt
• ¼ tsp black pepper
• 1 cup shredded mozzarella cheese (plus extra for topping)
• ¼ cup grated Parmesan cheese

Optional for Topping:

• Extra mozzarella or cheddar
• Chopped parsley or green onions
• Crushed red pepper flakes for a kick

Tools You’ll Need

• 9×13-inch casserole dish
• Medium skillet
• Mixing bowls
• Wooden spoon or spatula

Step-by-Step Instructions

Step 1: Preheat and Prep

1. Preheat your oven to 375°F (190°C).
2. Lightly grease a 9×13-inch baking dish.

Step 2: Sauté the Spinach

1. Heat olive oil in a skillet over medium heat.
2. Add garlic and sauté for 30 seconds until fragrant.
3. Add chopped spinach and cook for 2–3 minutes until wilted.
4. Remove from heat and set aside.

Step 3: Make the Creamy Sauce

1. In a mixing bowl, beat together cream cheese, sour cream, and chicken broth until smooth.
2. Stir in onion powder, garlic powder, salt, and pepper.
3. Mix in shredded chicken, cooked spinach, mozzarella, and Parmesan cheese.

Step 4: Assemble the Casserole

1. Pour the chicken and cream cheese mixture into the prepared baking dish.
2. Spread evenly and sprinkle with additional mozzarella cheese on top.

Step 5: Bake

1. Bake uncovered for 25–30 minutes, or until the casserole is hot and bubbly.
2. For a golden top, broil for the last 2–3 minutes, watching closely.

Step 6: Garnish and Serve

1. Let cool for 5 minutes before serving.
2. Garnish with chopped parsley or green onions if desired.

Tips for a Perfect Casserole
Use Cooked Chicken – Rotisserie chicken or pre-cooked breasts make this recipe extra easy.
Don’t Overcook Spinach – Just wilt it slightly to keep texture and color.
Soften Cream Cheese – Helps mix smoothly into the sauce.
Customize Your Cheese – Try gouda, Swiss, or pepper jack for different flavor twists.
Add Texture – Sprinkle breadcrumbs or crushed crackers on top if not low-carb.

Serving Suggestions
With Garlic Bread – A comforting, carb-y side for soaking up the sauce.
Over Rice or Pasta – Makes the dish even more filling.
With Roasted Veggies – Broccoli, zucchini, or green beans pair perfectly.
With a Side Salad – Light greens balance out the richness.
In Lettuce Wraps – A fun low-carb serving idea.

How to Store & Reheat

Storing:

• Refrigerate: Store in an airtight container for up to 4 days.
• Freeze: Cool completely and freeze for up to 2 months. Thaw in the fridge overnight before reheating.

Reheating:

• Oven: Reheat at 350°F (175°C) until warmed through, about 15–20 minutes.
• Microwave: Heat in 1-minute intervals, stirring between, until hot.

Frequently Asked Questions

1. Can I use frozen spinach?
Yes! Thaw and squeeze out excess moisture before adding it to the skillet.

2. Can I make this ahead of time?
Absolutely. Assemble the casserole and refrigerate it (covered) for up to 24 hours before baking.

3. Is this keto-friendly?
Yes! It’s naturally low in carbs and high in healthy fats and protein.

4. Can I add other vegetables?
Sure! Mushrooms, bell peppers, or zucchini are great additions—sauté them first for best results.

5. Can I use Greek yogurt instead of sour cream?
Yes! It’s a great substitute and adds a slight tang.

Final Thoughts
This Chicken and Spinach Casserole with Cream Cheese is comfort food done right—rich, cheesy, and packed with flavor, yet surprisingly easy to make. It’s a go-to recipe when you want something hearty and homemade that doesn’t take hours in the kitchen. Whether you’re cooking for the family or meal prepping for the week, this one’s a guaranteed winner.

Try it out and let me know what you think! Don’t forget to leave a review below and share your photos on Pinterest! I can’t wait to see how your casserole turns out.
Preparation Time: 15 minutes
Cooking Time: 30 minutes
Cuisine: American

Nutritional Information (Per Serving):
Calories: 420 | Protein: 31g | Carbohydrates: 5g | Fat: 30g | Fiber: 1g | Sodium: 480mg

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